axonal transport การใช้

• A second mechanism of reaching the brain tissue is achieved through intra-axonal transport.
• Studying this process is challenging, partly because anesthetising model organism also suspends axonal transport.
• Through this approach, live worm is immobilised in a chip and axonal transport studied.
• APLP2 has shown to act as a cargo receptor in axonal transport for intact proteins.
• There is evidence suggesting that it could be due to defects in the axonal transport of mitochondria.
• This insoluble structure damages cytoplasmic functions and interferes with axonal transport, which can lead to cell death.
• The mechanisms for the proliferation and sustained electrical potentials were affected by the fast axonal transport system.
• Recent research suggests that impaired axonal transport of alpha-synuclein leads to its accumulation in the Lewy bodies.
• Both the anterograde and retrograde tracing techniques are based on the visualization of the biological process of axonal transport.
• Generation of A? in the CNS may take place in the neuronal axonal membranes after APP-mediated axonal transport of ?-secretase and presenilin-1.
• It is thought that this protein may play a critical role in the development of axonal neuropathies resulting from impaired axonal transport.
• The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport.
• The composing cytoskeletal elements of axoplasm, neural filaments, and microtubules provide the framework for axonal transport which allows for neurotransmitters to reach the synapse.
• Semaphorins have also been shown to mediate other neuronal processes besides targeting such as : apoptosis, cell migration, axon pruning, synaptic transmission, and axonal transport.
• He and other researchers hooked up an " axonal transport facilitator " to a long molecule, and then attached drug molecules to the long tail.
• The retrograde axonal transport of the rabies virus to the CNS ( Central Nervous System ) is the key step of pathogenesis during natural infection.
• When an axon is damaged, both axonal translation and retrograde axonal transport are required to propagate a signal to the soma that the cell is damaged.
• Axonal transport is also responsible for moving molecules destined for degradation from the axon back to the cell body, where they are broken down by lysosomes.
• The fast axonal transport system uses the axoplasm for movement, and contains many non-conductive molecules that change the rate of these electrical potentials across the axon.
• The fast axonal transport system is able to function without an axolemma, implying that the electrical potential does not influence the transport of materials through the axon.